Cytocentric® Technology – Creating Optimal Environments for Cells
BioSpherix, Ltd. is a U.S. based biotechnology company at the forefront of advanced environmental control systems for cell culture, known for its proprietary Cytocentric® technology. Founded on the principle that cells deserve precise, physiologically relevant environments, BioSpherix designs and manufactures specialized, modular systems that tightly regulate oxygen, carbon dioxide, temperature, and humidity to support the most sensitive and demanding cellular research.
At the core of their innovation is the Xvivo System®, the only fully integrated, closed-chamber platform that offers real-time, automated control over multiple environmental variables mimicking in vivo-like conditions for in vitro cell culture. Unlike conventional incubators or laminar flow hoods, BioSpherix systems eliminate external fluctuations and contamination risk by allowing cells to remain continuously inside controlled, aseptic environments from seeding to analysis.
Key applications and advantages include:
Hypoxia Research: Precise oxygen control down to <1% O₂, critical for studying tumor microenvironments, ischemia, and stem cell behavior.
Stem Cell & Regenerative Medicine: Maintain physiologic conditions that promote proper differentiation, proliferation, and gene expression in pluripotent and adult stem cells.
Immunology & Cancer Research: Ideal for modeling immune-tumor interactions and simulating pathophysiological environments for drug testing.
Contamination-Free Workflow: Closed system eliminates cell exposure to ambient air, improving reproducibility and reducing variability.
The Xvivo System® is completely modular and scalable designed to adapt to laboratories of all sizes, from small academic labs to large-scale industrial and GMP facilities. Optional integrations include controlled gas mixers, HEPA filtration, hypoxia workstations, and live-cell imaging compatibility.
BioSpherix’s approach is cytocentric, shifting the focus from researcher convenience to what’s best for the cells. Their systems empower scientists to maintain stable, biologically relevant conditions, improving cell viability, data consistency, and experimental reproducibility.
With clients spanning top tier academic institutions, biotech companies, and pharmaceutical manufacturers, BioSpherix continues to play a vital role in enabling next-generation cell culture research, drug discovery, and cell therapy development.