The Microbial Genomics Experts Since 1993

Established in 1993, BaseClear has been a pioneer in genomic analysis, specializing in microbial genomics innovations and their industry applications. Located in the heart of the Leiden Bio Science Park in the Netherlands, one of Europe’s leading biomedical hubs, BaseClear offers a complete range of microbial genomics services, including genome sequencing and annotation, metagenomics, metatranscriptomics, microbiome analysis, and microbial strain characterization for regulatory approval.

Comprehensive Service Portfolio:
  • Genome-in-a-Week: BaseClear offers an ultra-fast service delivering fully assembled microbial genomes within five business days. Utilizing Oxford Nanopore Technologies (ONT), they provide assembled genomes for bacteria, yeast, fungi, phages, viruses, or plasmids, ensuring rapid and reliable results for various research applications.

  • Maternal & Infant Microbiome Analysis: Recognizing the critical role of early-life microbiota in long-term health, BaseClear provides extensive research solutions for maternal and infant microbiome studies. Their services encompass consultancy, study design, sampling solutions, sequencing, and comprehensive bioinformatic analyses to support advancements in maternal and infant health research.

  • Microbial Strain Typing: For root cause analysis of microbial contaminants or epidemiological purposes, BaseClear offers microbial strain typing services using methods such as Multi-locus sequence typing (MLST), repetitive element palindromic PCR (rep-PCR), and whole genome sequencing (WGS). These techniques enable precise tracking and tracing of microbial strains, aiding in quality control and contamination source identification. 

  • Rumen Microbiome Analysis: BaseClear provides end-to-end analysis and reporting services to gain insights into the rumen microbiome of ruminants like cows, sheep, and goats. Understanding the rumen microbiome is essential for improving feed conversion, animal health, and sustainable farming practices.

  • Methane Metabolism & Antimicrobial Screening: To assist in reducing methane emissions in livestock, BaseClear has developed an in-house methane metabolism pipeline. This service helps identify taxa, genes, and enzymes influencing methane production, supporting the development of interventions aimed at mitigating environmental impact.

BaseClear’s commitment to quality is underscored by their adherence to rigorous standards and the integration of advanced technologies to ensure precision and reproducibility in every project. Their team of over 65 highly educated and experienced specialists provides expert advice during project planning and implementation, ensuring optimal outcomes for clients.

By partnering with BaseClear, researchers and organizations gain access to a versatile and reliable collaborator dedicated to advancing the frontiers of microbial genomics and enabling groundbreaking discoveries.

BaseClear